1: Review with your students the components of Population Genetics and the Hardy-Weinberg Principle.

The Hardy-Weinberg Equilibrium describes the relationship between allele frequencies and genotype frequencies under the assumption of random mating.

To maintain this equilibrium, a number of assumptions must be met:

1. There must be no mutation
2. There must be no migration
3. Individuals must mate at random with respect to genotype
4. There must be no selection
5. The population must be infinitely large

The Hardy-Weinberg equation can be expressed as:
p + q = 1 or p2 + 2pq + q2 = 1

2: Have students complete the CSI Worksheet